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Zaključak
Važno je održavati visok stepen sumnje na ,,krpeljske” bolesti kod svih pacijenata koji se prezentuju
kožnom patologijom (posebno ako se vide pojedinačne lezije i eshare na mjestu uboda),
hepatosplenomegalijom, neurološkim ispadima, glavoboljom i sniženim brojem krvnih elemenata. U
relativno većem riziku su pacijenti koji su hipo- ili asplenični, ali i imunosuprimirani pacijenti. Kako je
lajmska bolest najčešća vektorska bolest na sjevernoj hemisferi, veoma je detaljno ispitana, te nema
opravdanja liječiti je naučno neutemeljenim metodologijama.
Abstract
Ticks are arthropods from the class Arachnida, related to spiders and mites. They can be found in a wide range of terrestrial
ecosystems and are obligate hematophagous ectoparasites of all vertebrates except fish. They cannot reproduce at high
altitudes and latitudes, and they are inactive during the winter. Ticks often live in symbiosis with bacteria such as Francisella
spp. and Coxiella spp. They go through four developmental stages, with nymphs and adults being the most significant
in the context of vectors for human pathogens. In Serbia, several species of ticks have been detected, including Ixodes
ricinus, Ixodes hexagonus, Dermacentor reticulatus, Dermacentor marginatus, Rhipicephalus sanguineus, Haemaphysalis
punctata, Haemaphysalis concinna, and Hyalomma marginatum. The most medically significant species is the common
tick (I. ricinus), which can transmit Lyme disease, anaplasmosis, relapsing fever, babesiosis, tick-borne encephalitis, and
orbivirus infections. Lyme disease, the most common vector-borne illness in the Northern Hemisphere, affects hundreds
of thousands of people annually. Other significant diseases transmitted by ticks include tularemia, TIBOLA (Tick-borne
Lymphadenopathy), Mediterranean spotted fever and Mediterranean spotted fever-like illnesses, Crimean-Congo
hemorrhagic fever, and Neoehrlichia mikurensis infection. The highest risk of complications is seen in patients who are
hypo- or asplenic, as well as immunosuppressed individuals. It is important to maintain a high index of suspicion for
tick-borne diseases in all patients presenting with a rash, hepatosplenomegaly, neurological deficits, headache, and/or a
reduced peripheral blood cell count.
Keywords: ticks, tick-borne diseases, arbovirus infections, Lyme disease, babesiosis
Literatura 8. Hauck D, Jordan D, Springer A, Schunack B, Pachnicke S, Fingerle V,
et al. Transovarial transmission of Borrelia spp., Rickettsia spp. and
Anaplasma phagocytophilum in Ixodes ricinus under field conditions
1. Giribet G. Current views on chelicerate phylogeny-A tribute to Peter extrapolated from DNA detection in questing larvae. Parasit Vectors.
Weygoldt. Zoologischer Anzeiger. 2018;273:7-13. 2020 Apr 7;13(1):176.
2. How do ticks…tick? Smithsonian Institution. Accessed October 9, 2021. 9. Scott JD. Presentation of Acrodermatitis Chronica Atrophicans Rashes
Available online: www.si.edu/stories/how-do-tickstick on Lyme Disease Patients in Canada. Healthcare (Basel). 2020 Jun
4;8(2):157.
3. Duron O, Gottlieb Y. Convergence of Nutritional Symbioses in Obligate
Blood Feeders. Trends Parasitol. 2020 Oct;36(10):816-25. 10. Eisen L. Pathogen transmission in relation to duration of attachment by
Ixodes scapularis ticks. Ticks Tick Borne Dis. 2018 Mar;9(3):535-42.
4. Wilhelmsson P, Jaenson TGT, Olsen B, Waldenström J, Lindgren PE.
Migratory birds as disseminators of ticks and the tick-borne pathogens 11. Harms MG, Hofhuis A, Sprong H, Bennema SC, Ferreira JA, Fonville M,
Borrelia bacteria and tick-borne encephalitis (TBE) virus: a seasonal et al. A single dose of doxycycline after an ixodes ricinus tick bite to
study at Ottenby Bird Observatory in South-eastern Sweden. Parasit prevent Lyme borreliosis: An open-label randomized controlled trial. J
Vectors. 2020 Dec 3;13(1):607. Infect. 2021 Jan;82(1):98-104.
5. CDC. Geographic distribution of ticks that bite humans | CDC. Centers 12. Steere A. Lyme Disease (Lyme Borreliosis) Due to Borrelia burgdorferi.
for Disease Control and Prevention. Published May 27, 2021. Accessed In: Mandell, Douglas, and Bennett’s Principles and Practice of Infectious
October 9, 2021. Available online: www.cdc.gov/ticks/geographic_ Diseases. 9th ed. Elsevier; 2020:2911-22.
distribution.html
13. Mahalingam M, Bhawan J, Eisen DB, Hu L. Lyme borreliosis. In:
6. CDC. Transmission of Lyme disease | CDC. Centers for Disease Control Fitzpatrick’s Dermatology in General Medicine. 8th ed. McGraw and Hill;
and Prevention. Published January 29, 2020. Accessed October 10, 2021. :2263-76.
Available online: www.cdc.gov/lyme/transmission/index.html 14. Association of Public Health Laboratories. Suggested Reporting
7. Breuner NE, Hojgaard A, Eisen L. Lack of Evidence for Transovarial Language, Interpretation and Guidance Regarding Lyme Disease
Transmission of the Lyme Disease Spirochete Borrelia mayonii by Serologic Test Results. Published online 2021. Accessed November
Infected Female Ixodes scapularis (Acari: Ixodidae) Ticks. J Med 6, 2021. Available online: www.aphl.org/aboutAPHL/publications/
Entomol. 2018 May 4;55(3):739-41. Documents/ID-2021-Lyme-Disease-Serologic-Testing-Reporting.pdf
70 DOI: 10.5937/Galmed2411059K

