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facet of age-related sarcopenia is the deterioration of type II fast-twitch muscle fibers, crucial for muscle strength and
overall performance.

Sarcopenia emerges as a syndrome characterized by progressive and generalized loss of skeletal muscle mass and
strength. It is inexorably linked with physical disability, diminished quality of life, and, notably, increased mortality rates.
Observational studies have indicated a substantial prevalence of sarcopenia among critically ill patients, affecting up to 60%
of individuals admitted to intensive care units, especially those requiring mechanical ventilation.

In light of these findings, this review aims to provide insights into the epidemiological, pathophysiological, and clinical
facets of sarcopenia. We underscore its particular relevance in the context of critically ill patients in intensive care
units, examining the profound impact on mortality. Furthermore, we delve into contemporary diagnostic methods for
identification and available treatment modalities, aiming to shed light on the complexities of this pervasive and under-
recognized condition.

Keywords: sarcopenia, muscle weakness, critical illness, intensive care unit, mortality

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