Page 47 - GALENIKA MEDICAL JOURNAL
P. 47
Abstract
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disease of the gastrointestinal tract of unclear
etiology. Based on the clinical, radiologic, endoscopic and histological features, there are two major forms of IBD: Crohn’s
disease (CD) and ulcerative colitis (UC). The medical treatment of IBD patients has changed drastically in the last decade
with the introduction of new targeted biologic therapies that complement the standard conventional therapy. Despite
the positive response to biological therapy, there are still shortcomings in this type of treatment. Nutrition has a vital
role in the management of inflammatory bowel disease. To improve nutrition problems and the quality of a patient’s life,
qualitative and quantitative dietary changes are needed. Clinical studies on probiotics in different clinical diseases have
shown different results. Still, it is evident that probiotics have displayed efficacy in preventing and treating various medical
conditions, particularly those involving the gastrointestinal tract.
Keywords: inflammatory bowel disease, diet, Crohn’s disease, ulcerative colitis, probiotics
Literatura 18. Workman EM, Alun Jones V, Wilson AJ, Hunter JO. Diet in the
management of Crohn's disease. Hum Nutr Appl Nutr. 1984
Dec;38(6):469-73.
1. Zhang YZ, Li YY. Inflammatory bowel disease: pathogenesis. World J 19. Durchschein F, Petritsch W, Hammer HF. Diet therapy for inflammatory
Gastroenterol. 2014 Jan 7;20(1):91-9. bowel diseases: The established and the new. World J Gastroenterol.
2. Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory 2016 Feb 21;22(7):2179-94.
bowel disease. J Clin Invest. 2007 Mar;117(3):514-21. 20. Caio G, Lungaro L, Caputo F, Zoli E, Giancola F, Chiarioni G, et al.
3. Seyedian SS, Nokhostin F, Malamir MD. A review of the diagnosis, Nutritional Treatment in Crohn's Disease. Nutrients. 2021 May
prevention, and treatment methods of inflammatory bowel disease. J 12;13(5):1628.
Med Life. 2019 Apr-Jun;12(2):113-22. 21. Coulson NS. How do online patient support communities affect the
4. Nikolaus S, Schreiber S. Diagnostics of inflammatory bowel disease. experience of inflammatory bowel disease? An online survey. JRSM
Gastroenterology. 2007 Nov;133(5):1670-89. Short Rep. 2013 Jul 1;4(8):2042533313478004.
5. Baumgart DC, Sandborn WJ. Inflammatory bowel disease: clinical 22. Nambisan P. Information seeking and social support in online health
aspects and established and evolving therapies. Lancet. 2007 May communities: impact on patients' perceived empathy. J Am Med Inform
12;369(9573):1641-57. Assoc. 2011 May 1;18(3):298-304.
6. Fuss IJ, Heller F, Boirivant M, Leon F, Yoshida M, Fichtner-Feigl S, et al. 23. Kozuch PL, Hanauer SB. Treatment of inflammatory bowel disease: a
Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize review of medical therapy. World J Gastroenterol. 2008 Jan 21;14(3):354-
an atypical Th2 response in ulcerative colitis. J Clin Invest. 2004 77.
May;113(10):1490-7. 24. Sandborn WJ, Targan SR. Biologic therapy of inflammatory bowel
7. McLeod RS. Surgery for inflammatory bowel diseases. Dig Dis. disease. Gastroenterology. 2002 May;122(6):1592-608.
2003;21(2):168-79. 25. Scaldaferri F, Pizzoferrato M, Lopetuso LR, Musca T, Ingravalle F,
8. De Greef E, Vandenplas Y, Hauser B, Devreker T, Veereman-Wauters G. Sicignano LL, et al. Nutrition and IBD: Malnutrition and/or Sarcopenia?
Probiotics and IBD. Acta Gastroenterol Belg. 2013 Mar;76(1):15-9. A Practical Guide. Gastroenterol Res Pract. 2017;2017:8646495.
9. Yamamoto T, Nakahigashi M, Saniabadi AR. Review article: diet and 26. de Onis M, Blössner M. The World Health Organization Global Database
inflammatory bowel disease--epidemiology and treatment. Aliment on Child Growth and Malnutrition: methodology and applications. Int J
Pharmacol Ther. 2009 Jul 1;30(2):99-112. Epidemiol. 2003 Aug;32(4):518-26.
10. Hou JK, Abraham B, El-Serag H. Dietary intake and risk of developing 27. Weisshof R, Chermesh I. Micronutrient deficiencies in inflammatory
inflammatory bowel disease: a systematic review of the literature. Am J bowel disease. Curr Opin Clin Nutr Metab Care. 2015 Nov;18(6):576-81.
Gastroenterol. 2011 Apr;106(4):563-73. 28. Jayawardena D, Dudeja PK. Micronutrient Deficiency in Inflammatory
11. Appleyard CB, Hernández G, Rios-Bedoya CF. Basic epidemiology of Bowel Diseases: Cause or Effect? Cell Mol Gastroenterol Hepatol.
inflammatory bowel disease in Puerto Rico. Inflamm Bowel Dis. 2004 2020;9(4):707-8.
Mar;10(2):106-11. 29. Smith MA, Smith T, Trebble TM. Nutritional management of adults
12. Yang SK, Yun S, Kim JH, Park JY, Kim HY, Kim YH, et al. Epidemiology with inflammatory bowel disease: practical lessons from the available
of inflammatory bowel disease in the Songpa-Kangdong district, evidence. Frontline Gastroenterol. 2012 Jul;3(3):172-9.
Seoul, Korea, 1986-2005: a KASID study. Inflamm Bowel Dis. 2008 30. Limdi JK. Dietary practices and inflammatory bowel disease. Indian J
Apr;14(4):542-9. Gastroenterol. 2018 Jul;37(4):284-92.
13. Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: 31. Maconi G, Ardizzone S, Cucino C, Bezzio C, Russo AG, Bianchi Porro
Incidence, prevalence, and environmental influences. Gastroenterology. G. Pre-illness changes in dietary habits and diet as a risk factor
2004 May;126(6):1504-17. for inflammatory bowel disease: a case-control study. World J
14. Hanauer SB. Inflammatory bowel disease: epidemiology, pathogenesis, Gastroenterol. 2010 Sep 14;16(34):4297-304.
and therapeutic opportunities. Inflamm Bowel Dis. 2006 Jan;12 Suppl 32. Sakamoto N, Kono S, Wakai K, Fukuda Y, Satomi M, Shimoyama T, et
1:S3-9. al; Epidemiology Group of the Research Committee on Inflammatory
15. Reif S, Klein I, Lubin F, Farbstein M, Hallak A, Gilat T. Pre-illness dietary Bowel Disease in Japan. Dietary risk factors for inflammatory bowel
factors in inflammatory bowel disease. Gut. 1997 Jun;40(6):754-60. disease: a multicenter case-control study in Japan. Inflamm Bowel Dis.
2005 Feb;11(2):154-63.
16. Morton H, Pedley KC, Stewart RJC, Coad J. Inflammatory Bowel Disease:
Are Symptoms and Diet Linked? Nutrients. 2020 Sep 29;12(10):2975. 33. Racine A, Carbonnel F, Chan SS, Hart AR, Bueno-de-Mesquita HB,
Oldenburg B, et al. Dietary Patterns and Risk of Inflammatory Bowel
17. Crooks B, McLaughlin J, Matsuoka K, Kobayashi T, Yamazaki H, Limdi JK. Disease in Europe: Results from the EPIC Study. Inflamm Bowel Dis.
The dietary practices and beliefs of people living with inactive ulcerative 2016 Feb;22(2):345-54.
colitis. Eur J Gastroenterol Hepatol. 2021 Mar 1;33(3):372-9.
REVIJALNI RADOVI Galenika Medical Journal, 2023; 2(5):41-46. 45

